The APRT antibody from MyBioSource.com is a Rabbit Polyclonal antibody to AMP, and aprt. This antibody recognizes Human antigen. The APRT antibody has been validated for the following applications: Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]